Early effects of high-fat diet on neurovascular function and focal ischemic brain injury

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Early effects of high-fat diet on neurovascular function and focal ischemic brain injury.

Obesity is a risk factor for stroke, but the early effects of high-fat diet (HFD) on neurovascular function and ischemic stroke outcomes remain unclear. The goal of this study was to test the hypotheses that HFD beginning early in life 1) impairs neurovascular coupling, 2) causes cerebrovascular dysfunction, and 3) worsens short-term outcomes after cerebral ischemia. Functional hyperemia and pa...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

سال: 2013

ISSN: 0363-6119,1522-1490

DOI: 10.1152/ajpregu.00523.2012